Nerve Pain Medication Explained

Know Your Nerve Pain Medication

The most commonly prescribed pharmaceutical nerve pain medication for neuropathy and nerve pain fall into three categories.

  1. Anticonvulsants/Anti-Seizure
  2. Anti-Depressants
  3. Narcotics

In reality, after reading through the treatment methods listed in the nerve pain medication list below, you will find that not one medication leads to a cure or helps to heal the nerves. With this in mind, the most effective modality of nerve pain medication only blocks the signals that trigger pain, they do not fix the cause of the pain.

Information about these medications are further detailed below.

Nerve Pain Medication

Anti-Convulsants & Anti-Seizure – Antiepileptic

Nerve Pain Medication

Risks and Benefits of Antiepileptic Drugs for Pain

Common Side Effects

The most common side effects for this category of nerve pain medication include: Dizziness, nausea, headache, vomiting, fatigue, vertigo, ataxia, blurred vision, and tremor.

Addiction is also a concern. Patients must be weaned or tapered off of these medications.

Falls are also associated with taking this type of medication due to its vertigo side effect. The loss of bone density is also noted in people taking these medications. Therefore the “fall” risk is not only elevated it is potentially more harmful due to bone density loss – especially for those individuals over the age of 65.

Suicidal thoughts and actions are also strongly associated with these medications.


It is not known exactly why these medications work to ease neuropathy and nerve pain. It is thought that they interfere with the over active nerve transmissions that the damaged nerve sends out and that this interference is what eases the pain.

Commonly Prescribed Antipileptic Drugs

Amitriptyline –  Brand Names: Elavil, Endep, Lentizol, Saroten, Tryptanol, and Tryptizol

Carbamazepine Brand Name: Tegretol

GabapentinBrand Name: Neurontin, Gabarone

OxcarbazepineBrand Names: Oxtellar XR, and Trileptal

PregabalinBrand Name: Lyrica

Topiramate, TopamaxBrand Names: Qudexy XR, Topamax, and Trokendi XR

Anti-Depressants – Selective Serotonin Reuptake Inhibitors (SSRIs)

Nerve Pain Medication

Risks and Benefits of Anti-depressants for Pain (SSRI)

Common Side Effects

The most common side effects associated with taking this type of nerve pain medication are: Drowsiness, nausea, dry mouth, insomnia, headache, diarrhea, blurred vision, nervousness, agitation or restlessness and dizziness.

Sexual problems, such as reduced sexual desire, difficulty reaching orgasm or inability to maintain an erection (erectile dysfunction)

Most notably, increased suicide rates and aggressive behavior risks have been further noted to accompany the use of these nerve pain medications. Read more here.

Addiction is indeed both psychological and physiological.

Withdrawal can consist of combinations of: Headaches, nausea, vomiting, stomach pains, cramps, and tremors.

Cardiovascular symptoms that include, increased blood pressure and increased heart rate.

Neurological symptoms, such as confusion and the potential to develop seizures.

Psychological symptoms that can include cravings, mood swings, depression, panic attacks, anxiety and what’s more, suicidal thoughts and actions.


SSRIs and nerve pain control still isn’t something that is fully understood. It is thought that antidepressants may increase the neurotransmitters in the spinal cord that work to reduce pain signals.

Specifically, this medication will not provide immediate results. A patient may feel relief in about 7 days, however to maximize the desired benefits, it may well take several weeks.

Taking SSRIs for nerve pain only provides moderate relief.

Commonly Prescribed SSRI Drugs

Alprazolam – Brand Names: Xanax XR, Niravam

Amitripyline – Brand Names: Elavil, Endep, Lentizol, Saroten, Tryptanol, and Tryptizol

Clonazepam – Brand Name: Klonopin

Clomipramine – Brand Name: Anafrani

CymbaltaBrand Names: Duzela, Yentreve, Xeristar, and Ariclaim

Diazepam – Brand Name: Valium

Desipramine – Brand Name: Norpramin


Duloxetine – Brand Name: Cymbalta

Imipramine – Brand Names: Tofranil and Tofranil PM

Nortriptyline – Brand Names:  Allegron, Aventyl, Noritren, Nortrilen, Pamelor & Others

FluoxetineBrand Names:  Prozac, Sarafem,

SertralineBrand Name: Zoloft

Paroxetine – Brand Names:  Brisdelle, Paxil, Paxil CR, Pexeva

Vilazodone – Brand Name: Viibryd

Narcotics – Opioids

Nerve Pain Medication

The Risks and Benefits of Opioids and Narcotics for Pain

Common Side Effects

The most common side effects from taking this type of nerve pain medication are: Sedation, dizziness, nausea, vomiting, constipation, physical dependence (addiction), tolerance, and respiratory depression.

Specifically, addiction to opioids is a high risk probability. As a result of addiction to this medication, opioid withdrawal symptoms may include: Muscle aches, restlessness, anxiety, eyes that tear up, runny nose, excessive sweating, inability to sleep, yawning very often, diarrhea, abdominal cramping, goose bumps on the skin, nausea and vomiting, dilated pupils and possibly blurry vision, rapid heartbeat, high blood pressure


There are, however some benefits to prescribing opioids for neuropathy and nerve pain. Methadone and levorphanol in particular, may act differently because they have unique mechanisms that drive the way that they interact with NMDA receptors. Similar to the interactions that antidepressants are reported to treat neuropathic pain – they specifically help block. (Here is a link to this study)

Opioids furthermore, are not the best treatment for neuropathy and nerve pain. They may actually help best for pain specifically created by nerve damage.

Commonly Prescribed Opioids and Narcotics for Nerve Pain

Codeine – Brand Names: Tylenol-Codeine No.3, Tylenol-Codeine No.4, Vopac

Fentanyl – Brand Names: (Actiq, Duragesic, Fentora, Abstral, Onsolis)

Hydrocodone – Brand Names: Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Tussionex Hysingla ER, Zohydro ER and Vicodin

Hydromorphone – Brand Names:  Dilaudid, Exalgo

Levorphanol – Brand Name: Levo-Dromoran

Meperidine –  Brand Name: Demerol

Methadone – Brand Names:  Dolophine, Methadose

 Morphine – Brand Names: Avinza, Kadian, MS Contin, MSIR, Oramorph, Morphabond

Oxycodone – Brand Names: Percodan, Endodan, Roxiprin, Percocet, Endocet, Roxicet, Oxaydo and OxyContin

Tramadol – Brand Names: Ultram, Conzip, Rybix ODT, and Ultram ER

Muscle Relaxers

Nerve Pain Medication

Risks and Benefits of Muscle Relaxers for Pain

Common Side Effects

Some of the most common side effects from taking muscle relaxers as nerve pain medication include: Problems breathing, light-headedness or fainting, blurred vision, confusion, nausea, sleepiness and urinary retention.

Furthermore, there is a potential for abuse of this medication. Continuous use of muscle relaxers however, can cause addiction. Muscle relaxers fast-acting quality can, unfortunately cause individuals to become dependent on them whenever they experience a measure of pain. Both physically and mentally addicting, this drug can become a patients “go to” for relaxation and/or pain relief.

Additionally, withdrawal from muscle relaxers can include: Nausea, headache, lethargy, chills, muscle aches, insomnia, sweating, anxiety, agitation, and irritability.


In addition to relaxing the muscles, muscle relaxers also help calm stabbing nerve pain. Muscle relaxers work, for example by stimulating receptors in the brain stem, which in turn reduces outflow from the central nervous system. As a result, this can cause a reduction in the feeling of nerve pain, it does not treat the root cause of the pain.

Commonly Prescribed Muscle Relaxers for Nerve Pain

Cyclobenzaprine Flexeril, Amrix, Cyclobenzaprine Comfort Pac Fexmid, FlexePax, FusePaq Tabradol, Therabenzaprine-60

Baclofen – Lioresal

Carisoprodol – Soma

Cyclobenzaprine – Amrix

Metaxalone – Skelaxin

Methocarbamol – Robaxin

Orphenadrine –  Norflex

Statin Drugs

Nerve Pain Medication

Risks of Taking Statin Drugs


Statin drugs are most commonly prescribed by doctors for cholesterol management, atheroma-related disease, and diabetes.   Peripheral neuropathy can result from taking Statin drugs which etch away at the myelin sheath surrounding the nerves. Furthermore, this erosion of the myelin sheath can eventually contribute to or even create the neuropathic pain that you suffer from. As a result, prescribed nerve pain medication for peripheral neuropathy may only compound the problem.

Additionally, Statin use side effects are: Headache, cataracts, pins and needles sensation, abdominal pain, bloating, diarrhea, feeling sick, a rash, impaired memory, liver failure and skeletal muscle damage.

Statins, are one of the most commonly prescribed medications in the world. Additionally, there is evidence that shows that they cause more harm than they do good. There is even more evidence that the Statins kill beneficial Co-Q 10 (Coenzyme Q 10) that helps promote clearing buildup in the veins and arteries, and furthermore it depletes the body of Vitamin K. Furthermore, there is evidence that cancer can occur with long term use.

Commonly Prescribed Statin Medication

Atorvastatin – Lipitor

Fuvastatin – Lescol, Lescol XL

Lovastatin – Mevacor, Altoprev

Pravastatin – Pravachol

Rosuvastatin – Crestor

Simvastatin – Zocor

Pitavastatin – Livalo

ReBuilder® Devices

Nerve Pain Medication

Our ReBuilder® devices are a holistic way to specifically treat neuropathy, nerve pain and painful numbness problems.

ReBuilder® Drug Free – Nerve Pain Relief – That Works!

ReBuilder® most notably, treats the nerves by restoring blood flow to the damaged nerves, thus feeding the nerves important minerals and more.

As a result, it helps nerves to regain their health by using its patented waveform. Read more here….


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