Conventional Neuropathy Pills and Their Consequences
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Conventional Neuropathy Pills & Their Consequences


neuropathy cause

Neuropathy is becoming a more common medical diagnosis every day. The condition features a wide range of symptoms for a single cause: nerve damage, which can be caused by a plethora of different medical conditions, or seemingly none at all! There are many different medications out there that treat your symptoms- and unfortunately, the side effects can feel like a new condition all on its own. If your doc can isolate your neuropathy's cause, they'll likely treat that condition first. As a patient, you should know what you are taking, edu­cate yourself about what these medications can and can't do, and learn what these neuropathy pills are actually prescribed for.

neuropathy pills side effects

Your nerves may have adapted to your affliction by contracting, which expands gaps between each nerve bundle. Normal nerve signals can't jump enlarged gaps. As a result, nerve impulses going to and from your brain, muscles, and blood vessels become blocked. Your brain is confused by the impaired signals, resulting in painful or conflicting sensations like feeling cold when warm, walk­ing on broken glass, pain, numbness, tingling, or burning.

The most commonly prescribed meds for neuropathic symptoms fall into 3 classifications: anticonvulsants/anti-seizure, antidepressants, and anesthetics/narcotics.

All three of these have a few things in common:

  • None have neuropathy as their primary reason for use
  • When used for neuropathy, it is only for pain
  • All will exacerbate numbness 
  • All come with a horribly long list of side-effects

The most effective function of conventional nerve pain medication is to block the pain signals, not fix the cause. Not one medication below leads to a cure or helps to heal the nerves.

Types of Nerve Pain Medication


  • Amitriptyline
  • Carbamazepine
  • Gabapentin
  • Oxcarbazepine
  • Pregabalin
  • Topiramate

Common Side Effects of Anti-Seizure / Anticonvulsant Meds

  • dizzi­ness
  • nausea
  • headache
  • vomiting
  • fatigue
  • vertigo
  • ataxia
  • blurred vision
  • tremor

Addiction is also a concern. Patients must be weaned or tapered off of these medica­tions. Falls are also associated with taking this type of medication due to its vertigo side effect. Bone density loss is also noted in people taking these medications. The "fall" risk is not only elevated but potentially more harmful- especially for those individuals over the age of 65. Suicidal thoughts and actions are also strongly associated with these medications.

Benefits of Anti-Seizure/Anticonvulsant Drugs

It is not known exactly why these medications work to ease neuropathy and nerve pain. It is thought that they interfere with the overactive nerve transmissions that the dam­aged nerve sends out and that this interference is what eases the pain.

Anti-Depressants (SSRI Drugs)

  • Alprazolam
  • Amitriptyline
  • Clonazepam
  • Clomipramine
  • Diazepam
  • Desipramine
  • Doxepin
  • Duloxetine
  • Imipramine
  • Nortriptyline
  • Fluoxetine
  • Sertraline
  • Paroxetine
  • Vilazodone

Common Side Effects of SSRIs

  • drowsiness
  • nausea
  • dry mouth
  • insomnia
  • headache
  • diarrhea
  • blurred vision
  • nerv­ousness
  • agitation or restlessness
  • dizziness
  • sexual problems, such as reduced sexual desire, difficulty reaching orgasm, or inabil­ity to maintain an erection (erectile dysfunction)
  • increased suicide rates and aggressive behavior risks have been fur­ther noted to accompany the use of these nerve pain medications
  • psychological and physiological addiction
  • withdrawal (can consist of combinations of headaches, nausea, vomiting, stomach pains, cramps, and tremors.)
  • cardiovascular symptoms (increased blood pressure and increased heart rate)
  • neurological symptoms, such as confusion and the potential to develop seizures
  • psychological symptoms can include cravings, mood swings, depression, panic attacks, anxiety, and what's more, suicidal thoughts and actions

Benefits of SSRIs

SSRIs and nerve pain control still aren’t something that is fully understood. It is thought that antidepressants may increase the neurotransmitters in the spinal cord that work to reduce pain signals. Specifically, this medication will not provide immediate results. A patient may feel relief in about 7 days, however, to maximize the desired benefits, it may take several weeks. Taking SSRIs for nerve pain only provides moderate relief.

Opioids and Narcotics

  • Codeine
  • Fentanyl
  • Hydrocodone
  • Hydromorphone
  • Levorphanol
  • Meperidine
  • Methadone
  • Morphine
  • Oxycodone
  • Tramadol

Opioid Side Effects

  • seda­tion
  • dizziness
  • nausea
  • vomiting
  • constipation
  • physical dependence (addiction)
  • toler­ance
  • respiratory depression
  • opioid withdrawal (muscle aches, restlessness, anxi­ety, eyes that tear up, runny nose, excessive sweating, inability to sleep, yawning very often, diarrhea, abdominal cramping, goosebumps on the skin, nausea, vomiting, dilated pupils, possibly blurry vision, rapid heartbeat, high blood pressure)

Benefits of Opioids

There are some benefits to prescribing opioids for neuropathy and nerve pain. Methadone and levorphanol may act differently because they have unique mechanisms that drive the way that they interact with NMDA receptors. Similar to the way antidepressants treat neuropathic pain, opioids help block.  


  • Baclofen
  • Carisoprodol
  • Cyclobenzaprine
  • Metaxalone
  • Methocarbamol
  • Orphenadrine

Muscle Relaxer Side Effects

  • problems breathing
  • light-headedness or fainting
  • blurred vision
  • confu­sion
  • nausea
  • sleepiness
  • urinary retention
  • withdrawal (nausea, headache, lethargy, chills, muscle aches, insomnia, sweating, anxiety, agitation, and irritability)

Furthermore, there is a potential for abuse of this medication. Continuous use of muscle relaxers, however, can cause addiction. Muscle relaxers’ fast-acting quality can unfortu­nately cause individuals to become dependent on them whenever they experience a measure of pain. Both physically and mentally addicting, this drug can become a patient’s "go-to" for relaxation and/or pain relief.

Muscle Relaxer Benefits

In addition to relaxing the muscles, muscle relaxers also help calm stabbing nerve pain. Muscle relaxers work by stimulating receptors in the brain stem, which reduces outflow from the central nervous system. This can cause a reduction in the feeling of nerve pain but does not treat the root cause of the pain.


  • Atorvastatin
  • Fluvastatin
  • Lovastatin
  • Pravastatin
  • Rosuvastatin
  • Simvastatin
  • Pitavastatin

Statin Side Effects

While not prescribed specifically for neuropathy, statin drugs are most commonly prescribed by doctors for cholesterol management, cardiovascular disease prevention, and diabetes. Once these drugs clear out the cholesterol from your arteries and veins, they go looking for other areas of cholesterol concentration. Peripheral neuropathy can result from taking statin drugs which eats away at the myelin sheath surrounding the nerves. Your nerves' myelin sheath is 27% pure cholesterol. This erosion of the myelin sheath can eventually contribute to or even create the neuropathic pain that you suffer from.

  • headache
  • cataracts
  • pins and needles sensation
  • abdominal pain
  • bloating
  • diarrhea
  • feeling sick
  • a rash
  • impaired memory
  • liver failure
  • skeletal muscle damage

Statins are one of the most commonly prescribed medications in the world. There is evidence that shows that they cause more harm than they do good. There is even more evidence that the statins kill beneficial Co-Q 10 (Coenzyme Q 10) that helps pro­mote clearing buildup in the veins and arteries, and it depletes the body of vitamin K (potassium).

Nerve Pain Treatment - More Reasons ReBuilder® Can Help

Neuropathy is truly debilitating, and a diagnosis can be daunting. Healthy habits cannot fix the nerves’ electrical problem alone. The ReBuilder® is a drug-free alternative to eliminate nerve pain imme­diately, and gently supports your body's healing process without causing further destruction. ReBuilder Medical is here to help you understand how to treat your neuropathy without dealing with the equally frustrating side effects of medication your doctor may have suggested. Give us a call and let's find a doctor near you to get started on a treatment plan!

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